Searchable abstracts of presentations at key conferences in endocrinology

ea0063p587 | Diabetes, Obesity and Metabolism 2 | ECE2019

Prevalence and characteristics of Nivolumab-induced diabetes: results from a monocentric observational study

Leclerc Helene , Drui Delphine , Mahot-Moreau Pascale , Pichelin Matthieu , Thomare Patrick , Landau Ester , Fournier Anne-Laure , Fronteau Clementine , Dresco Eric , Lucas-Pouliquen Bernadette , Cariou Bertrand

Introduction: Nivolumab is an anti-PD1 immunotherapy that restores the immune response against cancer cells, but can induce fulminant diabetes. The prevalence of such anti-PD1 induced diabetes is not clearly determined, but it has been recently estimated between 0.4% and 0.9% in recent studies. Here, we performed a monocentric epidemiological study in order to assess the prevalence and provide a description of Nivolumab-induced diabetes cases.Material an...